206367-33-1

206367-33-1 structure

Name: pBD-1
Chemical Name: pBD-1
CAS Number: 206367-33-1
Molecular Formula: C₃₁₀H₅₄₃N₉₁O₇₃S₁₁
Molecular Weight: 7065.98
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2020-06-01 08:40:56
Modify Date: 2024-01-02 14:35:14
pBD-1 is an endogenous and constitutively expressed antimicrobial peptide (AMP) from porcine tissues, particularly expresses in pig mucosal epithelial sites. pBD-1 has antimicrobial activities and contributes to mucosal and systemic host defenses in pigs[1].

Name	pBD-1

Description	pBD-1 is an endogenous and constitutively expressed antimicrobial peptide (AMP) from porcine tissues, particularly expresses in pig mucosal epithelial sites. pBD-1 has antimicrobial activities and contributes to mucosal and systemic host defenses in pigs[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
Target	IC50: bacterial[1]
In Vitro	In a northern blot analysis, pBD-1 mRNA only expresses in ongue epithelial tissues from 4-5 week old pigs[1]. In RT-PCR analysis, pBD-1 message throughout the epithelia of the respiratory (from nasal septum to lung) and gastrointestinal (from esophagus to rectum) tracts. In addition, it is detected in thymus, spleen, lymph node, brain, liver, kidney, urinary bladder, testis, skin, heart, muscle, bone marrow, alveolar macrophages, peripheral blood neutrophils and the umbilical cord. The only cells evaluated that does not express pBD-1 are peripheral blood mononuclear cells[1].
References	[1]. Zhang G, et al. Molecular cloning and tissue expression of porcine beta-defensin-1.FEBS Lett. 1998 Mar 6;424(1-2):37-40.

Molecular Formula	C₃₁₀H₅₄₃N₉₁O₇₃S₁₁
Molecular Weight	7065.98