pBD-1

Modify Date: 2024-01-02 14:35:14

pBD-1 Structure
pBD-1 structure
Common Name pBD-1
CAS Number 206367-33-1 Molecular Weight 7065.98
Density N/A Boiling Point N/A
Molecular Formula C310H543N91O73S11 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of pBD-1


pBD-1 is an endogenous and constitutively expressed antimicrobial peptide (AMP) from porcine tissues, particularly expresses in pig mucosal epithelial sites. pBD-1 has antimicrobial activities and contributes to mucosal and systemic host defenses in pigs[1].

 Names

Name pBD-1

 pBD-1 Biological Activity

Description pBD-1 is an endogenous and constitutively expressed antimicrobial peptide (AMP) from porcine tissues, particularly expresses in pig mucosal epithelial sites. pBD-1 has antimicrobial activities and contributes to mucosal and systemic host defenses in pigs[1].
Related Catalog
Target

IC50: bacterial[1]

In Vitro In a northern blot analysis, pBD-1 mRNA only expresses in ongue epithelial tissues from 4-5 week old pigs[1]. In RT-PCR analysis, pBD-1 message throughout the epithelia of the respiratory (from nasal septum to lung) and gastrointestinal (from esophagus to rectum) tracts. In addition, it is detected in thymus, spleen, lymph node, brain, liver, kidney, urinary bladder, testis, skin, heart, muscle, bone marrow, alveolar macrophages, peripheral blood neutrophils and the umbilical cord. The only cells evaluated that does not express pBD-1 are peripheral blood mononuclear cells[1].
References

[1]. Zhang G, et al. Molecular cloning and tissue expression of porcine beta-defensin-1.FEBS Lett. 1998 Mar 6;424(1-2):37-40.

 Chemical & Physical Properties

Molecular Formula C310H543N91O73S11
Molecular Weight 7065.98