Shanghai Nianxing Industrial Co., Ltd
China
Product Name: PEG20-Tos
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Purity: 96.0%
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2179113-08-5

2179113-08-5 structure

2179113-08-5 structure

Name: PEG20-Tos
Chemical Name: PEG20-Tos
CAS Number: 2179113-08-5
Molecular Formula: C₄₇H₈₈O₂₃S
Molecular Weight: 1053.25
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 12:19:24
Modify Date: 2024-01-22 11:38:57
PEG20-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	PEG20-Tos
Synonyms	MFCD29079389

Description	PEG20-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₄₇H₈₈O₂₃S
Molecular Weight	1053.25

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