PEG20-Tos

Modify Date: 2024-01-22 11:38:57

PEG20-Tos Structure
PEG20-Tos structure
Common Name PEG20-Tos
CAS Number 2179113-08-5 Molecular Weight 1053.25
Density N/A Boiling Point N/A
Molecular Formula C47H88O23S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PEG20-Tos


PEG20-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name PEG20-Tos
Synonym More Synonyms

 PEG20-Tos Biological Activity

Description PEG20-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C47H88O23S
Molecular Weight 1053.25

 Synonyms

MFCD29079389