Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Propargyl-peg4-sulfone-peg4-acid
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Purity: 98.0%
Stocking Period: 10 Day
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2055024-41-2

2055024-41-2 structure

2055024-41-2 structure

Name: Propargyl-PEG4-Sulfone-PEG4-acid
Chemical Name: Propargyl-PEG4-Sulfone-PEG4-acid
CAS Number: 2055024-41-2
Molecular Formula: C₂₂H₄₀O₁₂S
Molecular Weight: 528.61
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 09:46:07
Modify Date: 2024-01-10 21:32:42
Propargyl-PEG4-Sulfone-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Propargyl-PEG4-Sulfone-PEG4-acid
Synonyms	MFCD30182057

Description	Propargyl-PEG4-Sulfone-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₂₂H₄₀O₁₂S
Molecular Weight	528.61

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