Propargyl-PEG4-Sulfone-PEG4-acid

Modify Date: 2024-01-10 21:32:42

Propargyl-PEG4-Sulfone-PEG4-acid structure	Common Name	Propargyl-PEG4-Sulfone-PEG4-acid
	CAS Number	2055024-41-2	Molecular Weight	528.61
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₂H₄₀O₁₂S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Propargyl-PEG4-Sulfone-PEG4-acid

Propargyl-PEG4-Sulfone-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Propargyl-PEG4-Sulfone-PEG4-acid
Synonym	More Synonyms

Description	Propargyl-PEG4-Sulfone-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₂₂H₄₀O₁₂S
Molecular Weight	528.61

MFCD30182057

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