Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Propargyl-PEG6-thiol
Price:
Purity: 95.0%
Stocking Period: 10 Day
Contact: Yang

1422540-91-7

1422540-91-7 structure

1422540-91-7 structure

Name: Propargyl-PEG6-thiol
Chemical Name: Propargyl-PEG6-SH
CAS Number: 1422540-91-7
Molecular Formula: C₁₅H₂₈O₆S
Molecular Weight: 336.44
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 11:25:58
Modify Date: 2024-01-30 21:35:01
Propargyl-PEG6-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Propargyl-PEG6-SH

Description	Propargyl-PEG6-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula	C₁₅H₂₈O₆S
Molecular Weight	336.44