Propargyl-PEG6-thiol

Modify Date: 2024-01-30 21:35:01

Propargyl-PEG6-thiol structure	Common Name	Propargyl-PEG6-thiol
	CAS Number	1422540-91-7	Molecular Weight	336.44
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₅H₂₈O₆S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Propargyl-PEG6-thiol

Propargyl-PEG6-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Propargyl-PEG6-SH

Description	Propargyl-PEG6-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula	C₁₅H₂₈O₆S
Molecular Weight	336.44

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Propargyl-PEG6-thiol
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Purity: 95.0%
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