39637-78-0

39637-78-0 structure

39637-78-0 structure

Name: (R)-TCO-OH
Chemical Name: (R)-TCO-OH
CAS Number: 39637-78-0
Molecular Formula: C₈H₁₄O
Molecular Weight: 126.20
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 11:36:56
Modify Date: 2024-01-04 11:16:52
(R)-TCO-OH is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	(R)-TCO-OH

Description	(R)-TCO-OH is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	Alkyl-Chain
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula	C₈H₁₄O
Molecular Weight	126.20