2341796-78-7

2341796-78-7 structure
2341796-78-7 structure
  • Name: (S,R,S)-AHPC-C4-NH2 dihydrochloride
  • Chemical Name: (S,R,S)-AHPC-C4-NH2 dihydrochloride
  • CAS Number: 2341796-78-7
  • Molecular Formula: C27H41Cl2N5O4S
  • Molecular Weight: 602.62
  • Catalog: Signaling Pathways PROTAC E3 Ligase Ligand-Linker Conjugate
  • Create Date: 2020-06-01 21:04:46
  • Modify Date: 2024-01-16 15:52:10
  • (S,R,S)-AHPC-C4-NH2 dihydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and a linker used for EED-Targeted PROTAC[1].

Name (S,R,S)-AHPC-C4-NH2 dihydrochloride
Description (S,R,S)-AHPC-C4-NH2 dihydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and a linker used for EED-Targeted PROTAC[1].
Related Catalog
Target

VHL

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References

[1]. Hsu JH, et al. EED-Targeted PROTACs Degrade EED, EZH2, and SUZ12 in the PRC2 Complex. Cell Chem Biol. 2019 Nov 26. pii: S2451-9456(19)30362-9.

Molecular Formula C27H41Cl2N5O4S
Molecular Weight 602.62
Hazard Codes Xi