2341796-78-7

2341796-78-7 structure

Name: (S,R,S)-AHPC-C4-NH2 dihydrochloride
Chemical Name: (S,R,S)-AHPC-C4-NH2 dihydrochloride
CAS Number: 2341796-78-7
Molecular Formula: C₂₇H₄₁Cl₂N₅O₄S
Molecular Weight: 602.62
Catalog: Signaling Pathways PROTAC E3 Ligase Ligand-Linker Conjugate
Create Date: 2020-06-01 21:04:46
Modify Date: 2025-08-27 11:42:03
(S,R,S)-AHPC-C4-NH2 dihydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and a linker used for EED-Targeted PROTAC[1].

Name	(S,R,S)-AHPC-C4-NH2 dihydrochloride

Description	(S,R,S)-AHPC-C4-NH2 dihydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and a linker used for EED-Targeted PROTAC[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> E3 Ligase Ligand-Linker Conjugate
Target	VHL
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References	[1]. Hsu JH, et al. EED-Targeted PROTACs Degrade EED, EZH2, and SUZ12 in the PRC2 Complex. Cell Chem Biol. 2019 Nov 26. pii: S2451-9456(19)30362-9.

Molecular Formula	C₂₇H₄₁Cl₂N₅O₄S
Molecular Weight	602.62

Hazard Codes	Xi