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252378-68-0

252378-68-0 structure
252378-68-0 structure
  • Name: t-Boc-Aminooxy-PEG2-azide
  • Chemical Name: t-Boc-Aminooxy-PEG2-azide
  • CAS Number: 252378-68-0
  • Molecular Formula: C11H22N4O5
  • Molecular Weight: 290.32
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 17:38:36
  • Modify Date: 2024-01-16 18:41:40
  • t-Boc-Aminooxy-PEG2-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name t-Boc-Aminooxy-PEG2-azide
Description t-Boc-Aminooxy-PEG2-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C11H22N4O5
Molecular Weight 290.32