t-Boc-Aminooxy-PEG2-azide

Modify Date: 2024-01-16 18:41:40

t-Boc-Aminooxy-PEG2-azide Structure
t-Boc-Aminooxy-PEG2-azide structure
Common Name t-Boc-Aminooxy-PEG2-azide
CAS Number 252378-68-0 Molecular Weight 290.32
Density N/A Boiling Point N/A
Molecular Formula C11H22N4O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of t-Boc-Aminooxy-PEG2-azide


t-Boc-Aminooxy-PEG2-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name t-Boc-Aminooxy-PEG2-azide

 t-Boc-Aminooxy-PEG2-azide Biological Activity

Description t-Boc-Aminooxy-PEG2-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C11H22N4O5
Molecular Weight 290.32
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