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1797415-74-7

1797415-74-7 structure
1797415-74-7 structure
  • Name: TAMRA-Azide-PEG-Biotin
  • Chemical Name: TAMRA-Azide-PEG-biotin
  • CAS Number: 1797415-74-7
  • Molecular Formula: C57H79N11O14S
  • Molecular Weight: 1174.38
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 12:46:24
  • Modify Date: 2024-02-04 07:20:00
  • TAMRA-Azide-PEG-biotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name TAMRA-Azide-PEG-biotin
Description TAMRA-Azide-PEG-biotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C57H79N11O14S
Molecular Weight 1174.38