TAMRA-Azide-PEG-Biotin

Modify Date: 2024-02-04 07:20:00

TAMRA-Azide-PEG-Biotin Structure
TAMRA-Azide-PEG-Biotin structure
Common Name TAMRA-Azide-PEG-Biotin
CAS Number 1797415-74-7 Molecular Weight 1174.38
Density N/A Boiling Point N/A
Molecular Formula C57H79N11O14S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TAMRA-Azide-PEG-Biotin


TAMRA-Azide-PEG-biotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name TAMRA-Azide-PEG-biotin

 TAMRA-Azide-PEG-Biotin Biological Activity

Description TAMRA-Azide-PEG-biotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C57H79N11O14S
Molecular Weight 1174.38