TAMRA-Azide-PEG-Biotin

Modify Date: 2025-08-23 13:51:42

TAMRA-Azide-PEG-Biotin Structure
TAMRA-Azide-PEG-Biotin structure
Common Name TAMRA-Azide-PEG-Biotin
CAS Number 1797415-74-7 Molecular Weight 1174.38
Density N/A Boiling Point N/A
Molecular Formula C57H79N11O14S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TAMRA-Azide-PEG-Biotin


TAMRA-Azide-PEG-biotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name TAMRA-Azide-PEG-biotin

 TAMRA-Azide-PEG-Biotin Biological Activity

Description TAMRA-Azide-PEG-biotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C57H79N11O14S
Molecular Weight 1174.38
InChIKey OLNZJSRKGRJBHG-UHFFFAOYSA-N
SMILES CN(C)c1ccc2c(-c3cc(C(=O)NCCC(=O)N(CCOCCOCCOCCN=[N+]=[N-])CCC(=O)NCCOCCOCCOCCNC(=O)CCCCC4CC5NC(=O)NC5S4)ccc3C(=O)[O-])c3ccc(=[N+](C)C)cc-3oc2c1.CN(C)c1ccc2c(-c3ccc(C(=O)NCCC(=O)N(CCOCCOCCOCCN=[N+]=[N-])CCC(=O)NCCOCCOCCOCCNC(=O)CCCCC4CC5NC(=O)NC5S4)cc3C(=O)[O-])c3ccc(=[N+](C)C)cc-3oc2c1
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