1609736-43-7

1609736-43-7 structure
1609736-43-7 structure
  • Name: TCO-Amine HCl salt
  • Chemical Name: TCO-amine
  • CAS Number: 1609736-43-7
  • Molecular Formula: C12H22N2O2
  • Molecular Weight: 226.32
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 09:58:15
  • Modify Date: 2024-02-03 22:52:29
  • TCO-amine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name TCO-amine
Description TCO-amine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl-Chain

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C12H22N2O2
Molecular Weight 226.32