TCO-Amine HCl salt

Modify Date: 2024-02-03 22:52:29

TCO-Amine HCl salt Structure
TCO-Amine HCl salt structure
Common Name TCO-Amine HCl salt
CAS Number 1609736-43-7 Molecular Weight 226.32
Density N/A Boiling Point N/A
Molecular Formula C12H22N2O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TCO-Amine HCl salt


TCO-amine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name TCO-amine

 TCO-Amine HCl salt Biological Activity

Description TCO-amine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl-Chain

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C12H22N2O2
Molecular Weight 226.32