2211174-73-9

2211174-73-9 structure
2211174-73-9 structure
  • Name: Carboxy-PEG12-C2-Thiol
  • Chemical Name: Thiol-PEG12-acid
  • CAS Number: 2211174-73-9
  • Molecular Formula: C27H54O14S
  • Molecular Weight: 634.77
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 21:24:04
  • Modify Date: 2024-01-09 16:21:05
  • Thiol-PEG12-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Thiol-PEG12-acid
Description Thiol-PEG12-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C27H54O14S
Molecular Weight 634.77
Storage condition -20°C