1352914-52-3
1352914-52-3 structure
- Name: CR-1-31-B
- Chemical Name: CR-1-31-B
- CAS Number: 1352914-52-3
- Molecular Formula: C28H29NO8
- Molecular Weight: 507.53
- Catalog: Signaling Pathways Cell Cycle/DNA Damage Eukaryotic Initiation Factor (eIF)
- Create Date: 2020-08-08 15:02:19
- Modify Date: 2024-01-06 20:17:20
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CR-1-31-B is a potent eIF4A RNA helicase inhibitor. CR-1-31-B blocks MUC1-C translation in response to growth factor stimulation in breast cancer cells[1].
| Name | CR-1-31-B |
|---|
| Description | CR-1-31-B is a potent eIF4A RNA helicase inhibitor. CR-1-31-B blocks MUC1-C translation in response to growth factor stimulation in breast cancer cells[1]. |
|---|---|
| Related Catalog | |
| In Vitro | CR-1-31-B (100 nM; 24 hours) inhibits MUC1-C translation in MCF-10A cells[1]. CR-1-31-B (10 and 100 nM) decreases MUC1-C abundance in MDA-MB-468 breast cancer cells[1]. Western Blot Analysis[1] Cell Line: MCF-10A cells (EGF/HRG stimulated) Concentration: 100 nM Incubation Time: 24 hours Result: EGF-stimulated MCF-10A cells was associated with a dose-dependent decrease in MUC1-C abundance; Blocked HRG-induced increases in MUC1-C abundance. |
| References |
| Molecular Formula | C28H29NO8 |
|---|---|
| Molecular Weight | 507.53 |