CR-1-31-B
Modify Date: 2024-01-06 20:17:20
CR-1-31-B structure
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Common Name | CR-1-31-B | ||
|---|---|---|---|---|
| CAS Number | 1352914-52-3 | Molecular Weight | 507.53 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C28H29NO8 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of CR-1-31-BCR-1-31-B is a potent eIF4A RNA helicase inhibitor. CR-1-31-B blocks MUC1-C translation in response to growth factor stimulation in breast cancer cells[1]. |
| Name | CR-1-31-B |
|---|
| Description | CR-1-31-B is a potent eIF4A RNA helicase inhibitor. CR-1-31-B blocks MUC1-C translation in response to growth factor stimulation in breast cancer cells[1]. |
|---|---|
| Related Catalog | |
| In Vitro | CR-1-31-B (100 nM; 24 hours) inhibits MUC1-C translation in MCF-10A cells[1]. CR-1-31-B (10 and 100 nM) decreases MUC1-C abundance in MDA-MB-468 breast cancer cells[1]. Western Blot Analysis[1] Cell Line: MCF-10A cells (EGF/HRG stimulated) Concentration: 100 nM Incubation Time: 24 hours Result: EGF-stimulated MCF-10A cells was associated with a dose-dependent decrease in MUC1-C abundance; Blocked HRG-induced increases in MUC1-C abundance. |
| References |
| Molecular Formula | C28H29NO8 |
|---|---|
| Molecular Weight | 507.53 |