Shanghai Nianxing Industrial Co., Ltd
China
Product Name: EMI56
Price:
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang

DC Chemicals Limited
China
Product Name: EMI56
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

2414374-41-5

2414374-41-5 structure

2414374-41-5 structure

Name: EMI56
Chemical Name: EMI56
CAS Number: 2414374-41-5
Molecular Formula: C₂₁H₂₀N₂O₃
Molecular Weight: 348.40
Catalog: Signaling Pathways JAK/STAT Signaling EGFR
Create Date: 2020-08-10 20:31:33
Modify Date: 2024-01-02 10:37:04
EMI56, the derivative of EMI1, displays greater potency toward mutant EGFR than EMI1. EMI56 inhibits EGFR triple mutants[1].

Name	EMI56

Description	EMI56, the derivative of EMI1, displays greater potency toward mutant EGFR than EMI1. EMI56 inhibits EGFR triple mutants[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> EGFR Signaling Pathways >> Protein Tyrosine Kinase/RTK >> EGFR
Target	EGFRL858R/T790M/C797S EGFRdel19 T790M C797S
In Vitro	EMI56 inhibits EGFR ex19del/T790M/C797S and EGFR L858R/T790M/C797S. EMI56 can be used in the research of mutant EGFR-associated, drug-resistant non-small-cell lung cancer (NSCLC)[1].
References	[1]. Punit Saraon , et al. A Drug Discovery Platform to Identify Compounds That Inhibit EGFR Triple Mutants.Nat Chem Biol. 2020 May;16(5):577-586.

Molecular Formula	C₂₁H₂₀N₂O₃
Molecular Weight	348.40