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497932-19-1

497932-19-1 structure
497932-19-1 structure
  • Name: Ganglioside GD3 disodium salt
  • Chemical Name: Ganglioside GD3 disodium salt
  • CAS Number: 497932-19-1
  • Molecular Formula: C70H123N3Na2O29
  • Molecular Weight: 1516.71
  • Catalog: Signaling Pathways Others Others
  • Create Date: 2020-08-11 11:21:40
  • Modify Date: 2024-01-10 12:03:43
  • Ganglioside GD3 disodium salt is a melanoma-associated antigen and has been used as a target for the immune therapy of melanomas[1].

Name Ganglioside GD3 disodium salt
Description Ganglioside GD3 disodium salt is a melanoma-associated antigen and has been used as a target for the immune therapy of melanomas[1].
Related Catalog
In Vitro Ganglioside GD3 is highly expressed in melanomas in comparison with melanocytes, is exclusively expressed in the early developmental stage of the fetal brain, and is highly expressed in activated T lymphocytes and in T cell malignant tumor cells suggest that GD3 is involved in tumor phenotypes, such as enhanced proliferation and frequent metastasis[1].
References

[1]. Kazunori Hamamura, et al. Ganglioside GD3 promotes cell growth and invasion through p130Cas and paxillin in malignant melanoma cells. Proc Natl Acad Sci U S A. 2005 Aug 2;102(31):11041-6.

Molecular Formula C70H123N3Na2O29
Molecular Weight 1516.71