Ganglioside GD3 disodium salt

Modify Date: 2024-01-10 12:03:43

Ganglioside GD3 disodium salt Structure
Ganglioside GD3 disodium salt structure
Common Name Ganglioside GD3 disodium salt
CAS Number 497932-19-1 Molecular Weight 1516.71
Density N/A Boiling Point N/A
Molecular Formula C70H123N3Na2O29 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Ganglioside GD3 disodium salt


Ganglioside GD3 disodium salt is a melanoma-associated antigen and has been used as a target for the immune therapy of melanomas[1].

 Names

Name Ganglioside GD3 disodium salt

 Ganglioside GD3 disodium salt Biological Activity

Description Ganglioside GD3 disodium salt is a melanoma-associated antigen and has been used as a target for the immune therapy of melanomas[1].
Related Catalog
In Vitro Ganglioside GD3 is highly expressed in melanomas in comparison with melanocytes, is exclusively expressed in the early developmental stage of the fetal brain, and is highly expressed in activated T lymphocytes and in T cell malignant tumor cells suggest that GD3 is involved in tumor phenotypes, such as enhanced proliferation and frequent metastasis[1].
References

[1]. Kazunori Hamamura, et al. Ganglioside GD3 promotes cell growth and invasion through p130Cas and paxillin in malignant melanoma cells. Proc Natl Acad Sci U S A. 2005 Aug 2;102(31):11041-6.

 Chemical & Physical Properties

Molecular Formula C70H123N3Na2O29
Molecular Weight 1516.71