452274-53-2

452274-53-2 structure

Name: Human β-defensin-1
Chemical Name: Human β-defensin-1
CAS Number: 452274-53-2
Molecular Formula: C₁₆₇H₂₅₆N₄₈O₅₀S₆
Molecular Weight: 3928.53
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2020-08-11 12:50:38
Modify Date: 2025-08-25 16:01:30
Human β-defensin-1 (HβD-1) is a cysteine-rich cationic skin-antimicrobial peptide (SAP) produced by all epithelial surfaces, but also by circulatory cells and cells of the reproductive tract. Human β-defensin-1 has antimicrobial activities against a broad-sperm bacteria[1].

Name	Human β-defensin-1

Description	Human β-defensin-1 (HβD-1) is a cysteine-rich cationic skin-antimicrobial peptide (SAP) produced by all epithelial surfaces, but also by circulatory cells and cells of the reproductive tract. Human β-defensin-1 has antimicrobial activities against a broad-sperm bacteria[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
Target	IC50: skin-antimicrobial peptide (SAP)[1]
References	[1]. E V Valore, et al. Human beta-defensin-1: An Antimicrobial Peptide of Urogenital Tissues.J Clin Invest. 1998 Apr 15;101(8):1633-42. [2]. Judith Raschig, et al. Ubiquitously Expressed Human Beta Defensin 1 (hBD1) Forms Bacteria-Entrapping Nets in a Redox Dependent Mode of Action. PLoS Pathog. 2017 Mar 21;13(3):e1006261.

Molecular Formula	C₁₆₇H₂₅₆N₄₈O₅₀S₆
Molecular Weight	3928.53