Human β-defensin-1

Modify Date: 2024-01-10 17:01:30

Human β-defensin-1 Structure
Human β-defensin-1 structure
Common Name Human β-defensin-1
CAS Number 452274-53-2 Molecular Weight 3928.53
Density N/A Boiling Point N/A
Molecular Formula C167H256N48O50S6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Human β-defensin-1


Human β-defensin-1 (HβD-1) is a cysteine-rich cationic skin-antimicrobial peptide (SAP) produced by all epithelial surfaces, but also by circulatory cells and cells of the reproductive tract. Human β-defensin-1 has antimicrobial activities against a broad-sperm bacteria[1].

 Names

Name Human β-defensin-1

 Human β-defensin-1 Biological Activity

Description Human β-defensin-1 (HβD-1) is a cysteine-rich cationic skin-antimicrobial peptide (SAP) produced by all epithelial surfaces, but also by circulatory cells and cells of the reproductive tract. Human β-defensin-1 has antimicrobial activities against a broad-sperm bacteria[1].
Related Catalog
Target

IC50: skin-antimicrobial peptide (SAP)[1]

References

[1]. E V Valore, et al. Human beta-defensin-1: An Antimicrobial Peptide of Urogenital Tissues.J Clin Invest. 1998 Apr 15;101(8):1633-42.

[2]. Judith Raschig, et al. Ubiquitously Expressed Human Beta Defensin 1 (hBD1) Forms Bacteria-Entrapping Nets in a Redox Dependent Mode of Action. PLoS Pathog. 2017 Mar 21;13(3):e1006261.

 Chemical & Physical Properties

Molecular Formula C167H256N48O50S6
Molecular Weight 3928.53