1609937-15-6
1609937-15-6 structure
- Name: Mambalgin 1
- Chemical Name: Mambalgin 1
- CAS Number: 1609937-15-6
- Molecular Formula: C310H481N87O100S8
- Molecular Weight: 7283.22
- Catalog: Signaling Pathways Membrane Transporter/Ion Channel Sodium Channel
- Create Date: 2020-08-11 16:58:14
- Modify Date: 2024-01-12 22:42:42
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Mambalgin 1 is a selective ASIC1a inhibitor (IC50 values are 192 and 72 nM for human ASIC1a and ASIC1a/1b dimer, respectively). Mambalgin 1 binds to closed/inactive channel. Mambalgin 1 is selective for ASIC1a over ASIC2a, ASIC3, TRPV1, P2X2, 5-HT3, Nav1.8, Cav3.2 and Kv1.2 channels. Mambalgin 1 increases latency of withdrawal response in mouse tail-flick and paw-flick tests.
| Name | Mambalgin 1 |
|---|
| Description | Mambalgin 1 is a selective ASIC1a inhibitor (IC50 values are 192 and 72 nM for human ASIC1a and ASIC1a/1b dimer, respectively). Mambalgin 1 binds to closed/inactive channel. Mambalgin 1 is selective for ASIC1a over ASIC2a, ASIC3, TRPV1, P2X2, 5-HT3, Nav1.8, Cav3.2 and Kv1.2 channels. Mambalgin 1 increases latency of withdrawal response in mouse tail-flick and paw-flick tests. |
|---|---|
| Related Catalog |
| Molecular Formula | C310H481N87O100S8 |
|---|---|
| Molecular Weight | 7283.22 |