Shanghai Nianxing Industrial Co., Ltd
China
Product Name: ML233
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: ML233
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

2080311-92-6

2080311-92-6 structure

2080311-92-6 structure

Name: ML233
Chemical Name: ML233
CAS Number: 2080311-92-6
Molecular Formula: C₁₉H₂₁NO₄S
Molecular Weight: 359.44
Catalog: Research Areas Cardiovascular Disease
Create Date: 2020-08-10 20:38:04
Modify Date: 2024-01-08 09:51:45
ML233 is a non-peptide based potent apelin receptor (APJ) agonist (EC50=3.7 μM). ML233 displays >21-fold selective over the closely related angiotensin 1 (AT1) receptor (>79 μM)[1].

Name	ML233

Description	ML233 is a non-peptide based potent apelin receptor (APJ) agonist (EC50=3.7 μM). ML233 displays >21-fold selective over the closely related angiotensin 1 (AT1) receptor (>79 μM)[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Others >> Others
Target	EC50: 3.7 μM (Apelin receptor)[1]
In Vitro	ML233 shows potentially significant binding against several other receptors, including the 5-HT1A, α2C adrenergic, and benzylpiperazine receptors and norepinephrine transporter. ML233 shows some toxicity (LC50=25.8 μM) toward human hepatocyctes[1].
References	[1]. Khan P. National Center for Biotechnology Information; 2011. Functional agonists of the apelin (APJ) receptor. In Probe Reports from the NIH Molecular Libraries Program.

Molecular Formula	C₁₉H₂₁NO₄S
Molecular Weight	359.44

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