1627729-62-7

1627729-62-7 structure
1627729-62-7 structure
  • Name: MLK-IN-1
  • Chemical Name: MLK-IN-1
  • CAS Number: 1627729-62-7
  • Molecular Formula: C23H20N4O3S
  • Molecular Weight: 432.49
  • Catalog: Signaling Pathways MAPK/ERK Pathway Mixed Lineage Kinase
  • Create Date: 2020-08-09 17:15:33
  • Modify Date: 2024-01-04 16:12:07
  • MLK-IN-1 is a potent, brain penetrant and specific mixed lineage kinase 3 (MLK-3) inhibitor, compound 68, extracted from patent US20140256733A1[1].

Name MLK-IN-1
Description MLK-IN-1 is a potent, brain penetrant and specific mixed lineage kinase 3 (MLK-3) inhibitor, compound 68, extracted from patent US20140256733A1[1].
Related Catalog
Target

MLK3

In Vitro MLK-IN-1 (100 nM; pre-treatment 20 mins HIV-1 Tat) promotes continued axonogenesis in the presence of Tat-activated microglia and protects against effects of HIV-Tat in vitro[1].
References

[1]. Val S. Goodfellow,et al.Mixed lineage kinase inhibitors and method of treatments. Patent US20140256733A1.

Molecular Formula C23H20N4O3S
Molecular Weight 432.49