1627729-62-7

1627729-62-7 structure

1627729-62-7 structure

Name: MLK-IN-1
Chemical Name: MLK-IN-1
CAS Number: 1627729-62-7
Molecular Formula: C₂₃H₂₀N₄O₃S
Molecular Weight: 432.49
Catalog: Signaling Pathways MAPK/ERK Pathway Mixed Lineage Kinase
Create Date: 2020-08-09 17:15:33
Modify Date: 2024-01-04 16:12:07
MLK-IN-1 is a potent, brain penetrant and specific mixed lineage kinase 3 (MLK-3) inhibitor, compound 68, extracted from patent US20140256733A1[1].

Name	MLK-IN-1

Description	MLK-IN-1 is a potent, brain penetrant and specific mixed lineage kinase 3 (MLK-3) inhibitor, compound 68, extracted from patent US20140256733A1[1].
Related Catalog	Signaling Pathways >> MAPK/ERK Pathway >> Mixed Lineage Kinase Research Areas >> Neurological Disease
Target	MLK3
In Vitro	MLK-IN-1 (100 nM; pre-treatment 20 mins HIV-1 Tat) promotes continued axonogenesis in the presence of Tat-activated microglia and protects against effects of HIV-Tat in vitro[1].
References	[1]. Val S. Goodfellow,et al.Mixed lineage kinase inhibitors and method of treatments. Patent US20140256733A1.

Molecular Formula	C₂₃H₂₀N₄O₃S
Molecular Weight	432.49