Name | MM 54 |
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Description | MM 54 is a potent apelin receptor antagonist (Ki=82 nM, IC50=93 nM). MM 54 antagonizes the inhibitory affect of [Pyr1]-Apelin-13 on forskolin-induced cAMP accumulation in CHO-K1-APJ cells. MM 54 recuces tumor expansion and lengthens survival time in a mouse xenograft model of glioblastoma. |
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Related Catalog |
Molecular Formula | C70H121N29O15S4 |
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Molecular Weight | 1737.17 |