1313027-43-8
1313027-43-8 structure
- Name: MM 54
- Chemical Name: MM 54
- CAS Number: 1313027-43-8
- Molecular Formula: C70H121N29O15S4
- Molecular Weight: 1737.17
- Catalog: Signaling Pathways Others Others
- Create Date: 2020-08-10 19:56:56
- Modify Date: 2024-01-09 16:28:36
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MM 54 is a potent apelin receptor antagonist (Ki=82 nM, IC50=93 nM). MM 54 antagonizes the inhibitory affect of [Pyr1]-Apelin-13 on forskolin-induced cAMP accumulation in CHO-K1-APJ cells. MM 54 recuces tumor expansion and lengthens survival time in a mouse xenograft model of glioblastoma.
| Name | MM 54 |
|---|
| Description | MM 54 is a potent apelin receptor antagonist (Ki=82 nM, IC50=93 nM). MM 54 antagonizes the inhibitory affect of [Pyr1]-Apelin-13 on forskolin-induced cAMP accumulation in CHO-K1-APJ cells. MM 54 recuces tumor expansion and lengthens survival time in a mouse xenograft model of glioblastoma. |
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| Related Catalog |
| Molecular Formula | C70H121N29O15S4 |
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| Molecular Weight | 1737.17 |