MM 54

Modify Date: 2024-01-09 16:28:36

MM 54 Structure
MM 54 structure
Common Name MM 54
CAS Number 1313027-43-8 Molecular Weight 1737.17
Density N/A Boiling Point N/A
Molecular Formula C70H121N29O15S4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of MM 54


MM 54 is a potent apelin receptor antagonist (Ki=82 nM, IC50=93 nM). MM 54 antagonizes the inhibitory affect of [Pyr1]-Apelin-13 on forskolin-induced cAMP accumulation in CHO-K1-APJ cells. MM 54 recuces tumor expansion and lengthens survival time in a mouse xenograft model of glioblastoma.

 Names

Name MM 54

 MM 54 Biological Activity

Description MM 54 is a potent apelin receptor antagonist (Ki=82 nM, IC50=93 nM). MM 54 antagonizes the inhibitory affect of [Pyr1]-Apelin-13 on forskolin-induced cAMP accumulation in CHO-K1-APJ cells. MM 54 recuces tumor expansion and lengthens survival time in a mouse xenograft model of glioblastoma.
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 Chemical & Physical Properties

Molecular Formula C70H121N29O15S4
Molecular Weight 1737.17
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