1781834-82-9

1781834-82-9 structure

Name: PSN 375963 hydrochloride
Chemical Name: PSN 375963 hydrochloride
CAS Number: 1781834-82-9
Molecular Formula: C₁₇H₂₄ClN₃O
Molecular Weight: 321.84
Catalog: Signaling Pathways GPCR/G Protein GPR119
Create Date: 2020-08-07 18:49:45
Modify Date: 2024-01-12 21:50:28
PSN 375963 hydrochloride is a potent GPR119 agonist, with EC50s of 8.4 and 7.9 μM for human and mouse GPR119, respectively. PSN 375963 hydrochloride shows similar potency to the endogenous agonist oleoylethanolamide (OEA)[1][2].

Name	PSN 375963 hydrochloride

Description	PSN 375963 hydrochloride is a potent GPR119 agonist, with EC50s of 8.4 and 7.9 μM for human and mouse GPR119, respectively. PSN 375963 hydrochloride shows similar potency to the endogenous agonist oleoylethanolamide (OEA)[1][2].
Related Catalog	Research Areas >> Endocrinology Signaling Pathways >> GPCR/G Protein >> GPR119
References	[1]. Overton HA, et al. Deorphanization of a G protein-coupled receptor for oleoylethanolamide and its use in the discovery of small-molecule hypophagic agents. Cell Metab. 2006;3(3):167-175. [2]. Ning Y, et al. Endogenous and synthetic agonists of GPR119 differ in signalling pathways and their effects on insulin secretion in MIN6c4 insulinoma cells. Br J Pharmacol. 2008;155(7):1056-1065.

Molecular Formula	C₁₇H₂₄ClN₃O
Molecular Weight	321.84