PSN 375963 hydrochloride

Modify Date: 2024-01-12 21:50:28

PSN 375963 hydrochloride structure	Common Name	PSN 375963 hydrochloride
	CAS Number	1781834-82-9	Molecular Weight	321.84
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₇H₂₄ClN₃O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of PSN 375963 hydrochloride

PSN 375963 hydrochloride is a potent GPR119 agonist, with EC50s of 8.4 and 7.9 μM for human and mouse GPR119, respectively. PSN 375963 hydrochloride shows similar potency to the endogenous agonist oleoylethanolamide (OEA)[1][2].

Name	PSN 375963 hydrochloride

Description	PSN 375963 hydrochloride is a potent GPR119 agonist, with EC50s of 8.4 and 7.9 μM for human and mouse GPR119, respectively. PSN 375963 hydrochloride shows similar potency to the endogenous agonist oleoylethanolamide (OEA)[1][2].
Related Catalog	Research Areas >> Endocrinology Signaling Pathways >> GPCR/G Protein >> GPR119
References	[1]. Overton HA, et al. Deorphanization of a G protein-coupled receptor for oleoylethanolamide and its use in the discovery of small-molecule hypophagic agents. Cell Metab. 2006;3(3):167-175. [2]. Ning Y, et al. Endogenous and synthetic agonists of GPR119 differ in signalling pathways and their effects on insulin secretion in MIN6c4 insulinoma cells. Br J Pharmacol. 2008;155(7):1056-1065.

Description

Related Catalog

Research Areas >> Endocrinology

Signaling Pathways >> GPCR/G Protein >> GPR119

References

[1]. Overton HA, et al. Deorphanization of a G protein-coupled receptor for oleoylethanolamide and its use in the discovery of small-molecule hypophagic agents. Cell Metab. 2006;3(3):167-175.

[2]. Ning Y, et al. Endogenous and synthetic agonists of GPR119 differ in signalling pathways and their effects on insulin secretion in MIN6c4 insulinoma cells. Br J Pharmacol. 2008;155(7):1056-1065.

Molecular Formula	C₁₇H₂₄ClN₃O
Molecular Weight	321.84

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PSN 375963 hydrochloride

Use of PSN 375963 hydrochloride

Names

PSN 375963 hydrochloride Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.