Name | (S,R,S)-AHPC-C2-NH2 dihydrochloride |
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Description | (S,R,S)-AHPC-C2-NH2 dihydrochloride incorporates a VHL ligand for the E3 ubiquitin ligase, and a PROTAC linker. (S,R,S)-AHPC-OH can be used in the synthesis of a series of PROTACs[1]. |
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Related Catalog | |
Target |
VHL |
In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
References |
Molecular Formula | C25H37Cl2N5O4S |
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Molecular Weight | 574.56 |
Hazard Codes | Xi |
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