2138440-82-9

2138440-82-9 structure

Name: Thalidomide-NH-PEG3-propionic acid
Chemical Name: Thalidomide-NH-PEG3-propionic acid
CAS Number: 2138440-82-9
Molecular Formula: C₂₂H₂₇N₃O₉
Molecular Weight: 477.46
Catalog: Signaling Pathways PROTAC E3 Ligase Ligand-Linker Conjugate
Create Date: 2020-08-11 13:24:51
Modify Date: 2024-01-03 16:03:28
Thalidomide-NH-PEG3-propionic acid is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology[1].

Name	Thalidomide-NH-PEG3-propionic acid

Description	Thalidomide-NH-PEG3-propionic acid is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> E3 Ligase Ligand-Linker Conjugate
Target	Cereblon
References	[1]. David Remillard, et al. Degradation of the BAF Complex Factor BRD9 by Heterobifunctional Ligands.2017 May 15;56(21):5738-5743.

Molecular Formula	C₂₂H₂₇N₃O₉
Molecular Weight	477.46