Thalidomide-NH-PEG3-propionic acid

Modify Date: 2024-01-03 16:03:28

Thalidomide-NH-PEG3-propionic acid Structure
Thalidomide-NH-PEG3-propionic acid structure
Common Name Thalidomide-NH-PEG3-propionic acid
CAS Number 2138440-82-9 Molecular Weight 477.46
Density N/A Boiling Point N/A
Molecular Formula C22H27N3O9 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Thalidomide-NH-PEG3-propionic acid


Thalidomide-NH-PEG3-propionic acid is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology[1].

 Names

Name Thalidomide-NH-PEG3-propionic acid

 Thalidomide-NH-PEG3-propionic acid Biological Activity

Description Thalidomide-NH-PEG3-propionic acid is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology[1].
Related Catalog
Target

Cereblon

References

[1]. David Remillard, et al. Degradation of the BAF Complex Factor BRD9 by Heterobifunctional Ligands.2017 May 15;56(21):5738-5743.

 Chemical & Physical Properties

Molecular Formula C22H27N3O9
Molecular Weight 477.46