2229037-09-4
2229037-09-4 structure
- Name: TL 13-110
- Chemical Name: TL13-110
- CAS Number: 2229037-09-4
- Molecular Formula: C49H62ClN9O9S
- Molecular Weight: 988.59
- Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK ALK
- Create Date: 2020-08-09 16:29:45
- Modify Date: 2025-08-26 19:02:04
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TL13-110 is a negative control for TL13-112 (HY-123919) and a potent ALK inhibitor with an IC50 of 0.34 nM. TL13-110 does not degrade ALK in cells[1].
| Name | TL13-110 |
|---|
| Description | TL13-110 is a negative control for TL13-112 (HY-123919) and a potent ALK inhibitor with an IC50 of 0.34 nM. TL13-110 does not degrade ALK in cells[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 0.34 nM (ALK); 81 μM (Cereblon)[1] |
| In Vitro | TL13-110 also prompts the degradation of additional kinases including Aurora A, FER, PTK2 and RPS6KA1 with IC50 values of 9080 nM, 23.1 nM, 21.2 nM, and 480 nM, respectively. |
| References |
| Molecular Formula | C49H62ClN9O9S |
|---|---|
| Molecular Weight | 988.59 |