TL 13-110

Modify Date: 2024-01-14 00:33:14

TL 13-110 structure	Common Name	TL 13-110
	CAS Number	2229037-09-4	Molecular Weight	988.59
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₄₉H₆₂ClN₉O₉S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of TL 13-110

TL13-110 is a negative control for TL13-112 (HY-123919) and a potent ALK inhibitor with an IC50 of 0.34 nM. TL13-110 does not degrade ALK in cells[1].

Name	TL13-110

Description	TL13-110 is a negative control for TL13-112 (HY-123919) and a potent ALK inhibitor with an IC50 of 0.34 nM. TL13-110 does not degrade ALK in cells[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> ALK
Target	IC50: 0.34 nM (ALK); 81 μM (Cereblon)[1]
In Vitro	TL13-110 also prompts the degradation of additional kinases including Aurora A, FER, PTK2 and RPS6KA1 with IC50 values of 9080 nM, 23.1 nM, 21.2 nM, and 480 nM, respectively.
References	[1]. Chelsea E Powell, et al. Chemically Induced Degradation of Anaplastic Lymphoma Kinase (ALK). J Med Chem. 2018 May 10;61(9):4249-4255.

Molecular Formula	C₄₉H₆₂ClN₉O₉S
Molecular Weight	988.59

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: TL 13-110
Price: Negotiable
Purity: 98.0%
Delivery: 10 Day
Contact: Huang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: TL13-110
Price: $Inquiry/250mg $Inquiry/100mg $Inquiry/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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