TL 13-110
Modify Date: 2025-08-26 19:02:04
TL 13-110 structure
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Common Name | TL 13-110 | ||
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| CAS Number | 2229037-09-4 | Molecular Weight | 988.59 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C49H62ClN9O9S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of TL 13-110TL13-110 is a negative control for TL13-112 (HY-123919) and a potent ALK inhibitor with an IC50 of 0.34 nM. TL13-110 does not degrade ALK in cells[1]. |
| Name | TL13-110 |
|---|
| Description | TL13-110 is a negative control for TL13-112 (HY-123919) and a potent ALK inhibitor with an IC50 of 0.34 nM. TL13-110 does not degrade ALK in cells[1]. |
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| Related Catalog | |
| Target |
IC50: 0.34 nM (ALK); 81 μM (Cereblon)[1] |
| In Vitro | TL13-110 also prompts the degradation of additional kinases including Aurora A, FER, PTK2 and RPS6KA1 with IC50 values of 9080 nM, 23.1 nM, 21.2 nM, and 480 nM, respectively. |
| References |
| Molecular Formula | C49H62ClN9O9S |
|---|---|
| Molecular Weight | 988.59 |
| InChIKey | IJAANTOEOXWPKC-UHFFFAOYSA-N |
| SMILES | Cc1cc(Nc2ncc(Cl)c(Nc3ccccc3S(=O)(=O)C(C)C)n2)c(OC(C)C)cc1C1CCN(CCOCCOCCNC(=O)CNc2cccc3c2C(=O)N(C2CCCNC2=O)C3=O)CC1 |