1962928-23-9
1962928-23-9 structure
- Name: XAC
- Chemical Name: Xanthine amine congener dihydrochloride
- CAS Number: 1962928-23-9
- Molecular Formula: C21H30Cl2N6O4
- Molecular Weight: 501.41
- Catalog: Signaling Pathways GPCR/G Protein Adenosine Receptor
- Create Date: 2020-08-07 23:07:22
- Modify Date: 2024-01-10 23:06:37
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Xanthine amine congener dihydrochloride (XAC dihydrochloride) is a potent Adenosine A1 receptor and A2 receptor antagonist with IC50 values of 1.8 and 114 nM, respectively. Xanthine amine congener acts as a convulsant agent in mice model[1].
| Name | Xanthine amine congener dihydrochloride |
|---|
| Description | Xanthine amine congener dihydrochloride (XAC dihydrochloride) is a potent Adenosine A1 receptor and A2 receptor antagonist with IC50 values of 1.8 and 114 nM, respectively. Xanthine amine congener acts as a convulsant agent in mice model[1]. |
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| Related Catalog | |
| Target |
IC50: 1.8 nM (Adenosine A1 receptor) IC50: 114 nM (Adenosine A2 receptor)[1] |
| In Vivo | Xanthine amine congener dihydrochloride is more potent as a convulsant than either caffeine or theophyllin in infusion studies at the dosage 39.8 mg/kg. XAC has no effects by administering the drug via an i.p. injection, the seizure threshold >1000 mg/kg[1]. Animal Model: Mice[1] Dosage: 39.8 mg/kg Administration: Infusion injection; single dose Result: Acted as a convulsant agent than either caffeine or theophyllin. |
| References |
| Molecular Formula | C21H30Cl2N6O4 |
|---|---|
| Molecular Weight | 501.41 |