1129545-33-0

1129545-33-0 structure

Name: Hypocretin (70-98) (human)
Chemical Name: Hypocretin (70-98) (human)
CAS Number: 1129545-33-0
Molecular Formula: C₁₂₅H₂₁₄N₄₄O₃₇S
Molecular Weight: 2957.374
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2020-10-21 23:51:32
Modify Date: 2024-01-09 12:09:32
Hypocretin (70-98), human is a polypeptide that is capable of binding to an orexin receptor OX1R and promotes Apoptosis[1].

Name	Hypocretin (70-98) (human)
Synonyms	L-Arginyl-L-serylglycyl-L-prolyl-L-prolylglycyl-L-leucyl-L-glutaminylglycyl-L-arginyl-L-leucyl-L-glutaminyl-L-arginyl-L-leucyl-L-leucyl-L-glutaminyl-L-alanyl-L-serylglycyl-L-asparaginyl-L-histidyl-L-alanyl-L-alanylglycyl-L-isoleucyl-L-leucyl-L-threonyl-L-methionylglycine MFCD09264725 Glycine, L-arginyl-L-serylglycyl-L-prolyl-L-prolylglycyl-L-leucyl-L-glutaminylglycyl-L-arginyl-L-leucyl-L-glutaminyl-L-arginyl-L-leucyl-L-leucyl-L-glutaminyl-L-alanyl-L-serylglycyl-L-asparaginyl-L-histidyl-L-alanyl-L-alanylglycyl-L-isoleucyl-L-leucyl-L-threonyl-L-methionyl-

Description	Hypocretin (70-98), human is a polypeptide that is capable of binding to an orexin receptor OX1R and promotes Apoptosis[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> GPCR/G Protein >> Orexin Receptor (OX Receptor)
Target	human OX1R
In Vitro	Hypocretin (70-98), human 促进表达食欲素受体的细胞凋亡。 OX1R 促进癌细胞凋亡的机制与 Gq 介导的磷脂酶 C 激活和细胞钙瞬变无关。
References	[1]. Bruno Robert, et al. Polypeptides for preparing drug conjugates capable of promoting apoptosis in a cell expressing an orexin receptor. Patent WO2017140845A1.