- Taiwan Oyi peptide Co. Ltd
- China
- Product Name: MYELIN OLIGODENDROCYTE GLYCOPROTEIN (35-55) AMIDE (RAT, MOUSE) TRIFLUOROACETATE SALT
- Price: $Inquiry/1mg $Inquiry/100kg
- Purity: 98.0%
- Stocking Period: 1 Day
- Contact: Vinnie
2022956-48-3
2022956-48-3 structure
- Name: Myelin Oligodendrocyte Glycoprotein (35-55) amide (rat, mouse) trifluoroacetate salt
- Chemical Name: Myelin Oligodendrocyte Glycoprotein (35-55) amide (rat, mouse) trifluoroacetate salt
- CAS Number: 2022956-48-3
- Molecular Formula: C118H178N36O28S
- Molecular Weight: 2581
- Catalog: Research Areas Inflammation/Immunology
- Create Date: 2021-01-11 11:18:17
- Modify Date: 2024-01-16 21:15:17
-
MOG peptide (35-55) is a fragment 35-55 of myelin oligodendrocyte glycoprotein (MOG) immunogenic peptide. MOG peptide (35-55) is specific to expanded CD4+ T cells, and induces experimental autoimmune encephalomyelitis (EAE) in animal model[1][2][3].
| Name | Myelin Oligodendrocyte Glycoprotein (35-55) amide (rat, mouse) trifluoroacetate salt |
|---|
| Description | MOG peptide (35-55) is a fragment 35-55 of myelin oligodendrocyte glycoprotein (MOG) immunogenic peptide. MOG peptide (35-55) is specific to expanded CD4+ T cells, and induces experimental autoimmune encephalomyelitis (EAE) in animal model[1][2][3]. |
|---|---|
| Related Catalog | |
| In Vitro | The expanded CD4+ T cells are largely specific for the myelin oligodendrocyte glycoprotein (MOG) immunogenic peptide 35-55 (MOG35-55), while clonally expanded CD8+ T cells were non-responsive to myelin peptides or proteins[1]. |
| In Vivo | MOG peptide (35-55) (3 mg/mL for 0.1 mL; s.c.; single dose) results active induction of experimental autoimmune encephalomyelitis (EAE) in mice[2]. MOG peptide (35-55) (200 μg; s.c.; single dose) induces a increasing concentration of the eosinophil chemoattractant eotaxin-1 in the spinal cord in the course of EAE induced in C57BL/6 mice[3]. Animal Model: 129S1/SvImJ, C57BL/6 and C57BL/6 X SJL hybrid[2] Dosage: 3 mg/mL, 0.1 mL per mice; accompanied with CFA and 4 mg/mL Mycobacterium tuberculosis Administration: Subcutaneous injection; single dose Result: Showed the expected signs of experimental autoimmune encephalomyelitis (EAE), which started with tail loss of tonus and continued in an ascending fashion in mice immunized with MOG35-55. Animal Model: C57BL/6 mice (8-12 weeks)[3] Dosage: 200 μg Administration: Subcutaneous injection; single dose; analyzed at pre-onset (day 7 post immunization), onset (day 9-13 post immunization) and peak (day 17-19 post immunization) Result: Increased eosinophil abundance in the spinal cord increases in the course of EAE. |
| Molecular Formula | C118H178N36O28S |
|---|---|
| Molecular Weight | 2581 |