23050-38-6

23050-38-6 structure

Name: 5,7,8-Trimethoxyflavone
Chemical Name: 5,7,8-Trimethoxyflavone
CAS Number: 23050-38-6
Molecular Formula: C₁₈H₁₆O₅
Molecular Weight: 312.32
Catalog: Research Areas Inflammation/Immunology
Create Date: 2020-10-20 11:44:54
Modify Date: 2024-01-09 12:37:52
5,7,8-Trimethoxyflavone (Norwogonin 5,7,8-trimethyl ether), isolated from Andrographis echioides, inhibits NO with an IC50 of 39.1 μM. 5,7,8-Trimethoxyflavone has anti-inflammatory activity[1].

Name	5,7,8-Trimethoxyflavone

Description	5,7,8-Trimethoxyflavone (Norwogonin 5,7,8-trimethyl ether), isolated from Andrographis echioides, inhibits NO with an IC50 of 39.1 μM. 5,7,8-Trimethoxyflavone has anti-inflammatory activity[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
In Vitro	5,7,8-Trimethoxyflavone (Norwogonin 5,7,8-trimethyl ether; 8, 16, 32, 64 μM; for 24 hours) decreases NO production in a dose-dependent manner in RAW 264.7 macrophages. 5,7,8-Trimethoxyflavone does not change lipopolysaccharide (LPS)-induced (100 ng/mL) cell viability[1].
References	[1]. De-Yang Shen, et al. Chemical constituents from Andrographis echioides and their anti-inflammatory activity. Int J Mol Sci. 2012 Dec 27;14(1):496-514.