247044-67-3

247044-67-3 structure

Name: Insulin β Chain Peptide (15-23)
Chemical Name: Insulin β Chain Peptide (15-23)
CAS Number: 247044-67-3
Molecular Formula: C₄₄H₇₂N₁₂O₁₃S
Molecular Weight: 1009.18
Catalog: Research Areas Metabolic Disease
Create Date: 2021-01-11 12:06:52
Modify Date: 2025-08-23 18:09:50
Insulin β Chain Peptide (15-23), also known as INS, is an insulin-derived peptide recognized by islet-associated T cells. The Insulin β Chain Peptide (15-23) tetramer stained the INS-reactive CTL clone G9C8, but neither this tetramer nor the negative control tetramer (TUM) stained the splenic CD8+ T cells from NOD or 8.3-TCRαβtransgenic NOD mice[1][2].

Name	Insulin β Chain Peptide (15-23)

Description	Insulin β Chain Peptide (15-23), also known as INS, is an insulin-derived peptide recognized by islet-associated T cells. The Insulin β Chain Peptide (15-23) tetramer stained the INS-reactive CTL clone G9C8, but neither this tetramer nor the negative control tetramer (TUM) stained the splenic CD8+ T cells from NOD or 8.3-TCRαβtransgenic NOD mice[1][2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
References	[1]. Amrani A, et al. Progression of autoimmune diabetes driven by avidity maturation of a T-cell population. Nature. 2000;406(6797):739-742. [2]. Takaki T, et al. Requirement for both H-2Db and H-2Kd for the induction of diabetes by the promiscuous CD8+ T cell clonotype AI4. J Immunol. 2004;173(4):2530-2541.

Molecular Formula	C₄₄H₇₂N₁₂O₁₃S
Molecular Weight	1009.18