2122333-63-3

2122333-63-3 structure

Name: Tenofovir diphosphate triethylamine
Chemical Name: Tenofovir diphosphate triethylamine
CAS Number: 2122333-63-3
Molecular Formula: C₁₅H₃₁N₆O₁₀P₃
Molecular Weight: 548.36
Catalog: Signaling Pathways Anti-infection Reverse Transcriptase
Create Date: 2020-10-18 12:46:53
Modify Date: 2024-01-03 09:09:14
Tenofovir diphosphate triethylamine (TFV-DP triethylamine) is a competitive DNA polymerases inhibitor (with respect to dATP) and a substrate of HIV type 1 (HIV-1) reverse transcriptase (RT)[1].

Name	Tenofovir diphosphate triethylamine

Description	Tenofovir diphosphate triethylamine (TFV-DP triethylamine) is a competitive DNA polymerases inhibitor (with respect to dATP) and a substrate of HIV type 1 (HIV-1) reverse transcriptase (RT)[1].
Related Catalog	Research Areas >> Infection Research Areas >> Inflammation/Immunology Signaling Pathways >> Anti-infection >> Reverse Transcriptase
In Vitro	Tenofovir diphosphate acts as an inhibitor of DNA pol. Tenofovir-diphosphate is a weak inhibitor of DNA polymerases (pol) α, δ, and ɛ, with values for the Ki for PMPApp (PMPAppKi) relative to the Km for dATP (dATPKm) of 10.2, 10.2, and 15.6, respectively[1].
References	[1]. Gabriel Birkus, et al. Tenofovir Diphosphate Is a Poor Substrate and a Weak Inhibitor of Rat DNA Polymerases Alpha, Delta, and epsilon. Antimicrob Agents Chemother. 2002 May;46(5):1610-3.

Molecular Formula	C₁₅H₃₁N₆O₁₀P₃
Molecular Weight	548.36