792927-06-1

792927-06-1 structure

Name: TASIN-1
Chemical Name: TASIN-1
CAS Number: 792927-06-1
Molecular Formula: C₁₈H₂₈N₂O₃S
Molecular Weight: 352.491
Create Date: 2021-01-08 10:50:38
Modify Date: 2024-01-03 12:52:57
TASIN-1 is a selective inhibitor of truncated APC gene (adenomatous polyposis coli gene) and exerts cytotoxic effects through inhibition of cholesterol biosynthesis. TASIN-1 represents a potential therapeutic strategy for prevention and intervention in CRC with mutant APC[1].

Name	TASIN-1
Synonyms	1,4'-Bipiperidine, 1'-[(4-methoxyphenyl)sulfonyl]-4-methyl- 1'-[(4-Methoxyphenyl)sulfonyl]-4-methyl-1,4'-bipiperidine

Description	TASIN-1 is a selective inhibitor of truncated APC gene (adenomatous polyposis coli gene) and exerts cytotoxic effects through inhibition of cholesterol biosynthesis. TASIN-1 represents a potential therapeutic strategy for prevention and intervention in CRC with mutant APC[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Zhang L, et al. Selective targeting of mutant adenomatous polyposis coli (APC) in colorectal cancer. Sci Transl Med. 2016 Oct 19;8(361):361ra140.