1398053-45-6

1398053-45-6 structure

Name: CC 122 HCl
Chemical Name: Avadomide hydrochloride
CAS Number: 1398053-45-6
Molecular Formula: C₁₄H₁₅ClN₄O₃
Molecular Weight: 322.747
Create Date: 2021-01-01 02:17:37
Modify Date: 2025-08-27 17:24:45
Avadomide, also known as CC-122, is an orally available pleiotropic pathway modulator with potential antineoplastic activity. CC-122 mimics an interferon response and has antitumor activity in DLBCL CC-122 binds Cereblon (CRBN) and promotes degradation of Aiolos and Ikaros in diffuse large B-cell lymphoma (DLBCL) and T cells in vitro, in vivo, and in patients, resulting in both cell autonomous as well as immunostimulatory effects.

Name	Avadomide hydrochloride
Synonyms	3-(5-Amino-2-methyl-4-oxo-3(4H)-quinazolinyl)-2,6-piperidinedione hydrochloride (1:1) Avadomide hydrochloride 2,6-Piperidinedione, 3-(5-amino-2-methyl-4-oxo-3(4H)-quinazolinyl)-, hydrochloride (1:1) CC-122 HCl UNII:28DZS29F59