1807497-11-5
1807497-11-5 structure
- Name: Contezolid acefosamil
- Chemical Name: Acetyl hydrogen 1,2-oxazol-3-yl({(5R)-2-oxo-3-[2,3,5-trifluoro-4-(4-oxo-3,4-dihydro-1(2H)-pyridinyl)phenyl]-1,3-oxazolidin-5-yl}methyl)phosphoramidate
- CAS Number: 1807497-11-5
- Molecular Formula: C20H18F3N4O8P
- Molecular Weight: 530.348
- Create Date: 2021-01-06 22:15:23
- Modify Date: 2024-01-03 17:49:48
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Contezolid acefosamil (MRX-4) is the orally active prodrug of the active antimicrobial metabolite Contezolid (MRX-I), an oxazolidinone which shows potent in vitro activity against various multidrug-resistant Gram-positive bacteria, including MRSA
| Name | Acetyl hydrogen 1,2-oxazol-3-yl({(5R)-2-oxo-3-[2,3,5-trifluoro-4-(4-oxo-3,4-dihydro-1(2H)-pyridinyl)phenyl]-1,3-oxazolidin-5-yl}methyl)phosphoramidate |
|---|---|
| Synonyms |
Phosphoramidic acid, N-[[(5R)-3-[4-(3,4-dihydro-4-oxo-1(2H)-pyridinyl)-2,3,5-trifluorophenyl]-2-oxo-5-oxazolidinyl]methyl]-N-3-isoxazolyl-, monoacetyl ester
Acetyl hydrogen 1,2-oxazol-3-yl({(5R)-2-oxo-3-[2,3,5-trifluoro-4-(4-oxo-3,4-dihydro-1(2H)-pyridinyl)phenyl]-1,3-oxazolidin-5-yl}methyl)phosphoramidate |
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Boiling Point | 703.1±70.0 °C at 760 mmHg |
| Molecular Formula | C20H18F3N4O8P |
| Molecular Weight | 530.348 |
| Flash Point | 379.0±35.7 °C |
| Exact Mass | 530.081421 |
| LogP | -1.66 |
| Vapour Pressure | 0.0±2.3 mmHg at 25°C |
| Index of Refraction | 1.600 |