2055172-43-3

2055172-43-3 structure

Name: ML-226
Chemical Name: ML-226
CAS Number: 2055172-43-3
Molecular Formula: C₂₃H₂₆N₄O₂
Molecular Weight: 390.478
Catalog: Signaling Pathways Metabolic Enzyme/Protease MAGL
Create Date: 2021-01-07 18:33:06
Modify Date: 2024-01-17 08:17:27
ML226 is a potent α/β hydrolase domain-containing protein 11 (ABHD11) inhibitor in vitro and in situ with IC50s of 15 and 0.68 nM, respectively[1].

Name	ML-226
Synonyms	ML-226 Methanone, (2-ethyl-1-piperidinyl)[4-(hydroxydiphenylmethyl)-2H-1,2,3-triazol-2-yl]- (2-Ethyl-1-piperidinyl){4-[hydroxy(diphenyl)methyl]-2H-1,2,3-triazol-2-yl}methanone

Description	ML226 is a potent α/β hydrolase domain-containing protein 11 (ABHD11) inhibitor in vitro and in situ with IC50s of 15 and 0.68 nM, respectively[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> MAGL Research Areas >> Neurological Disease
References	[1]. Hsu KL, et al. Optimization and characterization of triazole urea inhibitors for abhydrolase domain containing protein 6 (ABHD6). 2012 Apr 12 [updated 2013 Mar 14]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–.