2100306-47-4
2100306-47-4 structure
- Name: N-(Amino-PEG1)-N-bis(PEG2-propargyl)
- Chemical Name: 6-{2-[2-(2-Propyn-1-yloxy)ethoxy]ethyl}-3,9,12-trioxa-6-azapentadec-14-yn-1-amine
- CAS Number: 2100306-47-4
- Molecular Formula: C18H32N2O5
- Molecular Weight: 356.457
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2021-01-07 18:26:28
- Modify Date: 2024-01-14 16:34:30
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N-(Amino-PEG1)-N-bis(PEG2-propargyl) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | 6-{2-[2-(2-Propyn-1-yloxy)ethoxy]ethyl}-3,9,12-trioxa-6-azapentadec-14-yn-1-amine |
|---|---|
| Synonyms |
6-{2-[2-(2-Propyn-1-yloxy)ethoxy]ethyl}-3,9,12-trioxa-6-azapentadec-14-yn-1-amine
MFCD30723225 3,9,12-Trioxa-6-azapentadec-14-yn-1-amine, 6-[2-[2-(2-propyn-1-yloxy)ethoxy]ethyl]- |
| Description | N-(Amino-PEG1)-N-bis(PEG2-propargyl) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 443.9±40.0 °C at 760 mmHg |
| Molecular Formula | C18H32N2O5 |
| Molecular Weight | 356.457 |
| Flash Point | 222.2±27.3 °C |
| Exact Mass | 356.231110 |
| LogP | -2.60 |
| Vapour Pressure | 0.0±1.1 mmHg at 25°C |
| Index of Refraction | 1.490 |