N-(Amino-PEG1)-N-bis(PEG2-propargyl)

Modify Date: 2024-01-14 16:34:30

N-(Amino-PEG1)-N-bis(PEG2-propargyl) structure	Common Name	N-(Amino-PEG1)-N-bis(PEG2-propargyl)
	CAS Number	2100306-47-4	Molecular Weight	356.457
	Density	1.1±0.1 g/cm3	Boiling Point	443.9±40.0 °C at 760 mmHg
	Molecular Formula	C₁₈H₃₂N₂O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	222.2±27.3 °C

Use of N-(Amino-PEG1)-N-bis(PEG2-propargyl)

N-(Amino-PEG1)-N-bis(PEG2-propargyl) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	6-{2-[2-(2-Propyn-1-yloxy)ethoxy]ethyl}-3,9,12-trioxa-6-azapentadec-14-yn-1-amine
Synonym	More Synonyms

Description	N-(Amino-PEG1)-N-bis(PEG2-propargyl) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

6-{2-[2-(2-Propyn-1-yloxy)ethoxy]ethyl}-3,9,12-trioxa-6-azapentadec-14-yn-1-amine

MFCD30723225

3,9,12-Trioxa-6-azapentadec-14-yn-1-amine, 6-[2-[2-(2-propyn-1-yloxy)ethoxy]ethyl]-

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