2219331-30-1
2219331-30-1 structure
- Name: BB-F-Yne
- Chemical Name: BB-F-Yne
- CAS Number: 2219331-30-1
- Molecular Formula: C28H26FN5O
- Molecular Weight: 467.537
- Create Date: 2021-01-07 19:28:41
- Modify Date: 2025-08-25 17:32:40
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BB-F-Yne is a cell-permeable derivative of the protein arginine diminase (PAD) inhibitor BB-Cl-amidine that contains an alkyne moiety for use in click chemistry reactions. BB-F-Yne inhibits PAD1-4 and has been used for labeling PADs in cell-free and cell-based assays, followed by click reactions with azide-modified TAMRA or biotin reporters.
| Name | BB-F-Yne |
|---|---|
| Synonyms |
N-{(1S)-1-(1H-Benzimidazol-2-yl)-4-[(2-fluoroethanimidoyl)amino]butyl}-4'-ethynyl-4-biphenylcarboxamide
[1,1'-Biphenyl]-4-carboxamide, N-[(1S)-1-(1H-benzimidazol-2-yl)-4-[(2-fluoro-1-iminoethyl)amino]butyl]-4'-ethynyl- BB-F-Yne |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Molecular Formula | C28H26FN5O |
| Molecular Weight | 467.537 |
| Exact Mass | 467.212128 |
| LogP | 3.87 |
| Index of Refraction | 1.627 |