688353-45-9
688353-45-9 structure
- Name: IWP 12
- Chemical Name: IWP-12
- CAS Number: 688353-45-9
- Molecular Formula: C18H18N4O2S3
- Molecular Weight: 418.556
- Create Date: 2021-01-30 08:12:23
- Modify Date: 2024-01-18 20:51:37
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IWP-12 is a potent inhibitor of porcupine (PORCN) and inhibits cell-autonomous Wnt signaling with an IC50 of 15 nM[1].
| Name | IWP-12 |
|---|---|
| Synonyms |
2-[(3,6-Dimethyl-4-oxo-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)sulfanyl]-N-(6-methyl-1,3-benzothiazol-2-yl)acetamide
Acetamide, N-(6-methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-3,6-dimethyl-4-oxothieno[3,2-d]pyrimidin-2-yl)thio]- IWP-12 |
| Description | IWP-12 is a potent inhibitor of porcupine (PORCN) and inhibits cell-autonomous Wnt signaling with an IC50 of 15 nM[1]. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Molecular Formula | C18H18N4O2S3 |
| Molecular Weight | 418.556 |
| Exact Mass | 418.059174 |
| LogP | 3.99 |
| Index of Refraction | 1.783 |
| RIDADR | NONH for all modes of transport |
|---|